There were multiple relations between the Veneto artist and the city of Bergamo.

It is not only the memory of a long stay, which began in 1513 with the Altar Piece of St. Bartholomew and ended in 1525 in the Stories of Mary in St. Michael at the White Well, with the ideal extension of the commitments taken for the intarsia of the choir of Santa Maria Maggiore: and not even the remark that there are many churches in Bergamo to be decorated with altarpieces by Lotto.

Even in the Province there are important testimony like the polyptych of Ponteranica and the Celana altarpiece, as well as the extraordinary cycle of frescoes of the Story of St. Barbara, in Trescore Balneario.